Extracellular Vesicles shuttle functional RNAs and genomic DNA which might be exploited as novel therapeutic targets or disease biomarkers in complex diseases, including cancer. HBM has developed optimized solutions for the efficient isolation of high-quality total RNA (miRNA and mRNAs) from the overall or from tumor-specific EV subpopulation, and of circulating and EV-associated genomic DNA. We offer:
EXO-TotalRNA: Overall Exosome Immunocapture and RNA extraction kit: Kit allows, by immunocapture, the isolation of overall exosome population from human biofluids or cell culture media and total RNA extraction.
TumorEXO-TotalRNA: Tumor Exosome Immunocapture and RNA extraction kit: Kit allows, by immunocapture, the enrichment of tumor-specific exosome population from human biofluids and total RNA extraction.
RNA Basic Kit: Kit allows total RNA extraction from exosomes pre-isolated with different methods (ultracentrifugation, chemical precipitation, immunocapture, size-chromatography etc.).
EXO-DNAc Kits: Isolation of circulating and EV-associated genomic DNA from biofluids and cell conditioned media.